Development and Validation of the B Cell-Associated Fc Receptor-like Molecule-Based Prognostic Signature in Skin Cutaneous Melanoma

Table 1

The results of GSEA analysis in high- and low-risk groups determined by FCRLs.

Pathway	Size	NES	NOM P value
High-risk group
KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS	25	1.997	<0.001
KEGG_RNA_POLYMERASE	29	1.849	0.008
KEGG_AMINOACYL_TRNA_BIOSYNTHESIS	41	1.848	0.008
KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM	16	1.726	0.014
KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS	11	1.611	0.03
KEGG_LYSINE_DEGRADATION	44	1.526	0.05
Low-risk group
KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION	258	-2.777	<0.001
KEGG_CHEMOKINE_SIGNALING_PATHWAY	186	-2.765	<0.001
KEGG_CELL_ADHESION_MOLECULES_CAMS	131	-2.716	<0.001
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY	130	-2.694	<0.001
KEGG_VIRAL_MYOCARDITIS	68	-2.647	<0.001
KEGG_JAK_STAT_SIGNALING_PATHWAY	151	-2.634	<0.001
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION	79	-2.578	<0.001
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION	116	-2.565	<0.001
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	101	-2.525	<0.001
KEGG_LEISHMANIA_INFECTION	69	-2.483	<0.001
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY	107	-2.478	<0.001
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS	131	-2.477	<0.001
KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS	95	-2.468	<0.001
KEGG_HEMATOPOIETIC_CELL_LINEAGE	85	-2.458	<0.001
KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY	61	-2.414	<0.001
KEGG_AUTOIMMUNE_THYROID_DISEASE	50	-2.39	<0.001
KEGG_APOPTOSIS	86	-2.34	<0.001
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY	74	-2.318	<0.001
KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY	79	-2.304	<0.001