Association between Single-Nucleotide Polymorphism in MicroRNA Target Site of DDB2 and Risk of Hepatocellular Carcinoma in a Southern Chinese Population
Table 3
Stratified analysis for the associations between DDB2 rs1050244 genotypes and HCC risk.
Variables
rs1050244 (cases/controls)
Adj OR (95% CI)
CC
CT/TT
CC vs. CT/TT
Age
0.195
≤48c
481/523
41/54
1.05 (0.52–2.14)
0.883
>48
509/483
42/59
0.60 (0.33–1.11)
0.103
Sex
0.928
Males
880/902
66/99
0.76 (0.46–1.26)
0.284
Females
110/104
17/14
0.74 (0.23–2.45)
0.625
Smoking
0.28
Never
566/780
59/86
0.91 (0.52–1.57)
0.728
Ever
424/226
24/27
0.56 (0.24–1.27)
0.164
Drinking
0.317
Never
597/802
58/92
0.88 (0.52–1.50)
0.646
Ever
393/204
25/21
0.59 (0.24–1.47)
0.258
HBV infection
0.002
(−)
168/896
6/109
0.31 (0.13–0.72)
0.006
(+)
822/110
77/4
2.50 (0.89–7.00)
0.082
aAdjusted for age, sex, smoking, drinking, and HBV infection in logistic regression models. value for interaction. cThe median age of this population.