Research Article

Association between Single-Nucleotide Polymorphism in MicroRNA Target Site of DDB2 and Risk of Hepatocellular Carcinoma in a Southern Chinese Population

Table 3

Stratified analysis for the associations between DDB2 rs1050244 genotypes and HCC risk.

Variablesrs1050244 (cases/controls)Adj OR (95% CI)
CCCT/TTCC vs. CT/TT

Age0.195
 ≤48c481/52341/541.05 (0.52–2.14)0.883
 >48509/48342/590.60 (0.33–1.11)0.103

Sex0.928
 Males880/90266/990.76 (0.46–1.26)0.284
 Females110/10417/140.74 (0.23–2.45)0.625

Smoking0.28
 Never566/78059/860.91 (0.52–1.57)0.728
 Ever424/22624/270.56 (0.24–1.27)0.164

Drinking0.317
 Never597/80258/920.88 (0.52–1.50)0.646
 Ever393/20425/210.59 (0.24–1.47)0.258

HBV infection0.002
 (−)168/8966/1090.31 (0.13–0.72)0.006
 (+)822/11077/42.50 (0.89–7.00)0.082

aAdjusted for age, sex, smoking, drinking, and HBV infection in logistic regression models. value for interaction. cThe median age of this population.