Potent In Vitro α-Glucosidase and β-Secretase Inhibition of Amyrin-Type Triterpenoid Isolated from Datura metel Linnaeus (Angel’s Trumpet) Fruits

Table 1

α-Glucosidase inhibitory activity of extract/fractions and isolated daturaolone (1).

Sample/standard	Concentration	% inhibition	(μM)
Hexane	0.2 μg	42.6	NA
Chloroform	0.2 μg	90.8
Ethyl acetate	0.2 μg	82.7
Methanol	0.2 μg	80.2
Daturaolone (1)	0.2 μM	98.7
Standard	0.2 μM	90.2

IC₅₀: minimum inhibitory concentration; SEM: standard error of mean; μM: micromolar; Standard: acarbose.