Research Article
AHNAK2 Is Associated with Poor Prognosis and Cell Migration in Lung Adenocarcinoma
Table 3
Univariate and multivariate Cox regression showed AHNAK2 could be an independent prognostic indicator.
| | TCGA-LUAD () | GSE72094 () | GSE26939 () | HR | 95% CI | value | HR | 95% CI | value | HR | 95% CI | value |
| Univariate | | | | | | | | | | Age | 1.006 | 0.990-1.023 | 0.449 | 1.497 | 1.028-2.181 | 0.035 | 1.023 | 0.997-1.049 | 0.085 | Gender | 1.032 | 0.752-1.416 | 0.845 | 1.009 | 0.989-1.029 | 0.389 | 1.67 | 0.982-2.838 | 0.058 | Stage | 1.693 | 1.464-1.957 | <0.001 | 1.653 | 1.383-1.976 | <0.001 | 1.317 | 0.984-1.764 | 0.064 | AHNAK2 | 1.038 | 1.022-1.054 | <0.001 | 1.251 | 1.083-1.445 | 0.002 | 1.147 | 1.034-1.273 | 0.009 |
| Multivariate | | | | | | | | | | Age | 1.008 | 0.993-1.024 | 0.292 | 1.614 | 1.097-2.375 | 0.015 | 1.024 | 0.996-1.053 | 0.093 | Gender | 0.93 | 0.674-1.282 | 0.656 | 1.004 | 0.984-1.024 | 0.716 | 1.358 | 0.779-2.367 | 0.281 | Stage | 1.695 | 1.462-1.966 | <0.001 | 1.694 | 1.408-2.038 | <0.001 | 1.337 | 0.977-1.83 | 0.069 | AHNAK2 | 1.038 | 1.020-1.056 | <0.001 | 1.207 | 1.050-1.387 | 0.008 | 1.135 | 1.028-1.253 | 0.012 |
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value < 0.05 was considered to be statistically significant. |