Aberrant Expression and Subcellular Localization of PER2 Promote the Progression of Oral Squamous Cell Carcinoma

Figure 3

PER2 inhibits OSCC cell proliferation, migration, and invasion in vitro. (a) Western blotting analysis of PER2 expression. (b) The monoclone of PER2-overexpressed CAL27 cells. (c) PER2 inhibited cell proliferation of CAL27 cells. (d and e) Growth of OSCC cells was detected using the clone formation assay. (f and g) Representative microphotographs of wound-healing assays. Black lines mark the migration front. (h and i) Representative microphotographs of invasion assays.

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