Contributions of Gene Modules Regulated by Essential Noncoding RNA in Colon Adenocarcinoma Progression

Figure 3

The comprehensive view of survival analysis features of group A and a case study (M2 module) of group A. (a) A comprehensive view of survival analysis features of group A. The first column represents the predictive ability for the survival of genes in group A modules. The second column represents the predictive ability of the survival of ncRNA-regulated modules in group A. Two columns were the -log10() of survival analysis. The numbers were colored based on the adjacent color map. The details of these results for the M2 module are shown in (b) and (c). (b) Subnetwork of the predictive ability for the survival of genes of the M2 module. Nodes are colored as stage III COAD-DEGs, stage IV COAD-DEGs, or overlap genes of stage III COAD-DEGs and stage IV COAD-DEGs. Node size is shown according to its network degree. The differences in the survival times were analyzed using the log rank test. The value for survival analysis was 0.01944. (c) Subnetwork and the predictive ability for survival of genes and ncRNAs of the M2 module. Nodes are colored as stage III COAD-DEGs, stage IV COAD-DEGs, overlap genes of stage III COAD-DEGs and stage IV COAD-DEGs, and pivot miRNA and pivot lncRNA of the M2 module. Node size is shown according to its network degree. The differences in the survival times were analyzed using the log rank test. The value for survival analysis was 5.0175-05.