Contributions of Gene Modules Regulated by Essential Noncoding RNA in Colon Adenocarcinoma Progression

Table 1

Statistics about ncRNA-regulated module 2.

lncRNA (PMID)	miRNA (PMID)	Gene	value^&	value^#	value (dataset)
LINC00630 (28473661, 25908452), RP11-452F19.3, XIST (31452526, 28730777, 29504606)	Let-7f-5p (29805607), miR-7-5p (30867755), miR-18a-5p (30458288), miR-18b-5p (30458288), miR-26b-5p (28640257), miR-103a-3p (30458288), miR-106b-5p (30013364), miR-122-5p (28177881), miR-130a-p (28849155), miR-140-5p (31011255), miR-155-5p (2947100), miR-196a-5p (30621631), miR-301a-3p (30362160), miR-301b-3p (20132431), miR-362-3p (23280316), miR-590-3p (28938537), miR-590-5p (27735951)	A2M, ABL1, ACACB, ACVR2A, ACVR2B, ADCY2, ADSSL1, AGTR2, ATIC, BAMBI, BMP2, BMPR1A, BMPR1B, BMPR2, CACNA1C, CACNA1D, CACNA1F, CACNA1G, CACNA1H, CACNA1S, CACNA2D1, CACNB1, CACNB2, CACNB3, CACNB4, CDK5, CDT1, CHRD, CHRM5, CHUK, CLOCK, CRMP1, CRY1, CRY2, CSF2, CSNK1E, CXCR4, DPYSL3, DRD5, E2F1, EPHA3, EPHA5, EPHA6, EPHA7, F2RL3, FANCD2, FANCI, FOXO1, FOXO3, FST, FZD4, FZD5, FZD7, FZD8, GPER1, HGF, HPRT1, HRH4, HTR2B, IKBKB, INS-IGF2, IRS2, LPAR1, LPAR3, MCHR1, MED1, MED21, MED23, MED27, MED4, MET, MRE11A, MTNR1B, MYD88, NCOA1, NOG, NPAS2, P2RY13, PCNA, PDE4A, PDE4B, PDE4C, PDE4D, PER1, PER2, PIK3CB, PIK3R1, PLCG1, POMC, PPARGC1A, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKACA, PRKACB, PRKAG1, PRKAG2, PRKAG3, PSMD11, PSMD6, PTGS2, QRFPR, RAC1, RAD17, RAD21, RAD50, RAD51C, RBBP8, S1PR1, S1PR2, S1PR3, SMAD2, SMAD5, SMAD9, SMC1B, SMC3, SMURF1, SMURF, SP1, SPO11, STAG2, STAT3, STK11, SYCE1, SYCE2, SYCP1, SYCP2, SYCP3, TEX12, TGFB3, TGFBR1, TGFBR2, TIMELESS, TOPBP1, UTS2R, WNT1, WNT2, WNT3, WNT3A, WNT5A, YES1	5.02-05	0.0194	0.0015 (GSE29623), 2.20-16 (GSE39582), 2.20-16 (GSE17563)

value is used to measure the overall survival of COAD patients by Kaplan-Meier analysis. & and # stand for the value of M2 with or without ncRNA regulators from TCGA data and stands for the value of M2 without ncRNA regulators in three other independent datasets from GEO. The numbers in the parentheses are PubMed IDs (PMID).