Effect of THBS1 on the Biological Function of Hypertrophic Scar Fibroblasts

Figure 2

THBS1 promotes the growth and migration of hypertrophic scar cells. (a) Cell proliferation was assessed using MTT assays in hypertrophic scar cells 24 h after transfection with a vector or THBS1. . (b) Apoptosis was detected using annexin V-PI assays in hypertrophic scar cells 24 h after transfection with a vector or THBS1. . (c) Cell migration was determined using Transwell assays in hypertrophic scar cells 24 h after transfection with a vector or THBS1. . Original magnification ×200. (d, e) THBS1 and TGF-β1 expression in hypertrophic scar cells transfected with a vector (vec) or THBS1. .

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