Integrated Bioinformatics Analysis of the Clinical Value and Biological Function of ATAD2 in Hepatocellular Carcinoma

Figure 1

IHC staining of ATAD2 in HCC tissues and expression and prognosis of ATAD2 in HCC based on TCGA and our institutional data. Positive immunohistochemical reaction was showed as brown staining. Representative tissue sections with different immunochemical staining status (from nucleus to negative) of ATAD2: (a) nucleus: poorly differentiated; (b) cytoplasm: moderately poorly differentiated; (c) less cytoplasm: moderately differentiated; (d) negative: well differentiated. For each intensity group, the specimens were obtained (×200 and ×400 magnification). (e) Scatter plot of ATAD2 expression at different races. (f) Scatter plot of ATAD2 expression based on family cancer history. (g) Scatter plot of ATAD2 expression at different histological grades. (h) Overall survival of HCC patients related to ATAD2 status (protein level) in institutional data. (i) Disease-free survival of HCC patients related to ATAD2 status (protein level) in institutional data. (j) Overall survival of HCC patients related to ATAD2 status (mRNA level) based on TCGA data.

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