Integrated Bioinformatics Analysis of the Clinical Value and Biological Function of ATAD2 in Hepatocellular Carcinoma

Table 1

Characteristics of datasets included in this study.

First author (publication year)	Country/region	Dataset	Platform	Samples	Cancer			Nontumor
					N	Mean	SD	N	Mean	SD
Kim B et al. (2009)	South Korea	GEO:GSE14811	KRIBB GLP8177	Pair-matched HCC vs. adjacent liver tissues	56	-0.040	0.033	56	0.111	0.034
Ozturk M et al. (2009)	Turkey	GEO:GSE17548	Affymetrix GPL570	Cirrhosis liver vs HCC	17	7.967	0.267	20	6.968	0.148
Archer KJ et al. (2009)	USA	GEO:GSE17967	Affymetrix GPL571	Cirrhosis liver with or without HCC	16	6.477	0.179	47	5.768	0.094
Bonacci B et al. (2010)	USA	GEO:GSE22045	Affymetrix GPL570	Pair-matched HCC vs. adjacent liver tissues	24	6.034	0.191	24	5.047	0.051
Zhang C et al. (2010)	USA	GEO:GSE25097	Affymetrix GPL10687	Cirrhotic and normal livers vs HCC	268	2.818	0.109	289	0.788	0.024
Huang Y et al. (2011)	Taiwan	GEO:GSE33006	Affymetrix GPL570	Pair-matched HCC vs. adjacent liver tissues	3	10.150	0.209	3	8.246	0.160
Lim HY et al. (2012)	South Korea	GEO:GSE36376	Illumina GPL10558	Pair-matched HCC vs. adjacent liver tissues	240	7.576	0.040	193	6.806	0.016
Kim J et al. (2012)	USA	GEO:GSE39791	Illumina GPL10558	Pair-matched HCC vs. adjacent liver tissues	72	7.636	0.055	72	7.106	0.028
Darpolor MM et al. (2013)	USA	GEO:GSE45050	Affymetrix GPL6244	Cirrhotic and normal livers vs HCC	6	8.532	0.406	10	7.683	0.141
Wei L et al. (2013)	China	GEO:GSE45114	CapitalBio GPL5918	Normal vs. HCC and pericancer tissues	24	1.341	0.226	25	-0.086	0.171
Jeng Y et al. (2013)	Taiwan	GEO:GSE46408	Agilent GPL4133	Pair-matched HCC vs. adjacent liver tissues	6	10.210	0.386	6	7.636	0.221
Chen X et al. (2013)	USA	GEO:GSE46444	Illumina GPL13369	Liver tissues vs. HCC from HCC patients	88	7.478	0.106	48	7.961	0.139
Geffers R et al. (2013)	Germany	GEO:GSE50579	Agilent GPL14550	Liver cell and normal liver vs. HCC	70	10.500	0.126	10	9.037	0.118
Villa E et al. (2014)	Italy	GEO:GSE54236	Agilent GPL6480	Pair-matched HCC vs. adjacent liver tissues	81	7.534	0.119	80	6.689	0.077
Melis M et al. (2014)	USA	GEO:GSE55092	Affymetrix GPL570	Cirrhosis liver vs HCC	49	7.016	0.119	91	6.132	0.034
Hoshida Y et al. (2014)	USA	GEO:GSE56140	Illumina GPL18461	Cirrhosis liver vs HCC	35	8.806	0.106	34	7.991	0.044
Mah W et al. (2014)	Singapore	GEO:GSE57957	Illumina GPL10558	Pair-matched HCC vs. adjacent liver tissues	39	9.173	0.123	39	8.410	0.067
Udali S et al. (2014)	Italy	GEO:GSE59259	NimbleGen GPL18451	Alcohol-cirrhosis liver vs HCC	8	10.490	0.310	8	10.710	0.145
Kao KJ et al. (2014)	Taiwan	GEO:GSE60502	Affymetrix GPL96	Pair-matched HCC vs. adjacent liver tissues	18	9.241	0.209	18	7.808	0.101
Zucman-Rossi J et al. (2014)	France	GEO:GSE62232	Affymetrix GPL570	Normal vs. HCC	81	7.569	0.131	10	6.013	0.130
Makowska Z et al. (2014)	Switzerland	GEO:GSE64041	Affymetrix GPL6244	Normal vs. HCC	60	7.589	0.111	65	6.796	0.043
Tao Y et al. (2015)	China	GEO:GSE74656	Affymetrix GPL16043	Pair-matched HCC vs. adjacent liver tissues	10	6.990	0.278	5	5.727	0.173
Grinchuk OV et al. (2015)	Singapore	GEO:GSE76427	Illumina GPL10558	Pair-matched HCC vs. adjacent liver tissues	115	8.656	0.064	52	8.009	0.065
Qin W et al. (2016)	China	GEO:GSE84402	Affymetrix GPL570	Pair-matched HCC vs. adjacent liver tissues	14	6.801	0.312	14	5.086	0.247
Hui KM et al. (2018)	Singapore	GEO:GSE121248	Affymetrix GPL570	Cirrhosis liver vs HCC	70	8.041	0.111	37	6.893	0.126
Wurmbach E et al. (2007)	USA	Oncomine:Wurmbach liver	Affymetrix GPL570	Cirrhosis liver vs. HCC and relapse tissues	35	8.049	0.234	40	6.263	0.088
Mas VR et al. (2009)	USA	Oncomine:Mas liver	Affymetrix GPL96	Cirrhosis liver vs. HCC and relapse tissues	64	6.463	0.109	60	6.080	0.084

Abbreviation: SD: standard deviation.