Research Article
Integrated Bioinformatics Analysis of the Clinical Value and Biological Function of ATAD2 in Hepatocellular Carcinoma
Table 2
Distribution of ATAD2 and clinicopathological characteristics from institutional HCC patients.
| Characteristics | No. of patients | ATAD2 | | | Low expression | High expression |
| Tissue | | | | | | Tumor | 80 | 28 | 52 | 8.046 | 0.006 | Normal tumor | 20 | 14 | 6 | | | Gender | | | | | | Male | 66 | 25 | 41 | 1.374 | 0.357 | Female | 14 | 3 | 11 | | | Age (year) | | | | | | <50 | 25 | 7 | 18 | 0.783 | 0.454 | ≥50 | 55 | 21 | 34 | | | Tumor size | | | | | | ≥5 cm | 35 | 7 | 28 | 6.154 | 0.018 | <5 cm | 45 | 21 | 24 | | | Metastasis | | | | | | Yes | 30 | 5 | 25 | 7.092 | 0.009 | No | 50 | 23 | 27 | | | Invasion | | | | | | Yes | 27 | 6 | 21 | 2.925 | 0.136 | No | 53 | 22 | 31 | | | Cirrhosis | | | | | | Yes | 76 | 27 | 49 | 0.185 | 1.000 | No | 4 | 1 | 3 | | | HBsAg | | | | | | Positive | 64 | 22 | 42 | 0.055 | 1.000 | Negative | 16 | 6 | 10 | | | AFP | | | | | | <200 ng/dl | 57 | 25 | 32 | 6.841 | 0.010 | ≥200 ng/dl | 23 | 3 | 20 | | | TNM stage | | | | | | I + II | 50 | 22 | 28 | 4.747 | 0.033 | III + IV | 30 | 6 | 24 | | | Differentiation | | | | | | WD | 35 | 16 | 19 | 3.391 | 0.184 | MD | 35 | 10 | 25 | | | PD | 10 | 2 | 8 | | |
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Abbreviations: WD: well differentiated; MD: moderately differentiated; PD: poorly differentiated.
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