Antioxidant and Antiproliferative Potential of Bioactive Molecules Ursolic Acid and Thujone Isolated from Memecylon edule and Elaeagnus indica and Their Inhibitory Effect on Topoisomerase II by Molecular Docking Approach
Table 6
Antioxidant activities IC50/EC50 values of ursolic acid and thujone.
Assays
IC50/EC50 values (μg/mL)
Ursolic acid
Thujone
Ascorbic acid
BHA
DPPH radical
71.86 ± 0.54
60.92 ± 1.61
18.77 ± 0.52
15.48 ± 0.61
FRAP
18.42 ± 0.03
44.58 ± 0.89
33.62 ± 0.61
11.24 ± 0.37
Hydroxyl radical
29.69 ± 0.44
49.47 ± 0.62
20.47 ± 0.86
40.78 ± 0.98
Nitric oxide radical
70.40 ± 0.08
77.68 ± 0.58
36.43 ± 0.71
53.90 ± 0.64
Superoxide radical
43.35 ± 0.95
131.78 ± 1.27
67.03 ± 0.80
90.84 ± 1.76
The values are mean of triplicates with standard deviation (mean ± S.D; n = 3).