Research Article

Antioxidant and Antiproliferative Potential of Bioactive Molecules Ursolic Acid and Thujone Isolated from Memecylon edule and Elaeagnus indica and Their Inhibitory Effect on Topoisomerase II by Molecular Docking Approach

Table 6

Antioxidant activities IC50/EC50 values of ursolic acid and thujone.

AssaysIC50/EC50 values (μg/mL)
Ursolic acidThujoneAscorbic acidBHA

DPPH radical71.86 ± 0.5460.92 ± 1.6118.77 ± 0.5215.48 ± 0.61
FRAP18.42 ± 0.0344.58 ± 0.8933.62 ± 0.6111.24 ± 0.37
Hydroxyl radical29.69 ± 0.4449.47 ± 0.6220.47 ± 0.8640.78 ± 0.98
Nitric oxide radical70.40 ± 0.0877.68 ± 0.5836.43 ± 0.7153.90 ± 0.64
Superoxide radical43.35 ± 0.95131.78 ± 1.2767.03 ± 0.8090.84 ± 1.76

The values are mean of triplicates with standard deviation (mean ± S.D; n = 3).