Blood Monocyte Phenotype Fingerprint of Stable Coronary Artery Disease: A Cross-Sectional Substudy of SMARTool Clinical Trial
Table 3
Univariate and multivariate multinomial logistic regression analyses of Mon2 markers (% positivity% and RFI).
Mon2 markers
Comparison between groups
Univariate regression coefficient
Unadjusted OR
95% CI
Adjusted ORa
95% CI
CX3CR1 (RFI)
CAD1/CAD2 CAD1/CAD3
0.014 0.015
1.014 1.015
0.996-1.032 0.998-1.033
Ns Ns
1.055 1.057
1.009-1.103 1.008-1.108
0.0187 0.0215
CD18 (RFI)
CAD1/CAD2 CAD1/CAD3
0.008 0.005
1.008 1.005
0.997-1.020 0.994-1.016
Ns Ns
1.030 1.028
1.005-1.055 1.002-1.054
0.0197 0.0338
HLA-DR (RFI)
CAD1/CAD2 CAD1/CAD3
0.011 0.006
1.012 1.006
0.997-1.026 0.993-1.019
Ns Ns
1.028 1.029
0.998-1.059 0.999-1.060
Ns Ns
CXCR4 (RFI)
CAD1/CAD2 CAD1/CAD3
0.011 0.013
1.011 1.013
0.997-1.025 0.999-1.027
Ns Ns
1.002 1.016
0.980-1.023 0.993-1.040
Ns Ns
CCR2 (RFI)
CAD1/CAD2 CAD1/CAD3
0.014 0.005
1.014 1.005
1.001-1.027 0.992-1.017
0.0402 Ns
1.036 1.026
1.011-1.061 0.997-1.056
0.0042 Ns
CD163 (RFI)
CAD1/CAD2 CAD1/CAD3
0.025 0.009
1.025 1.009
1.005-1.045 0.992-1.026
0.0126 Ns
1.037 1.031
1.004-1.071 0.993-1.069
0.0297 Ns
CD16 (%+)
CAD1/CAD2 CAD1/CAD3
0.116 0.171
1.123 1.187
0.972-1.298 1.030-1.367
Ns 0.0179
1.341 1.463
1.021-1.761 1.051-2.037
0.0352 0.0240
CAD: coronary artery disease; OR: odds ratio; CI: confidence interval; Ns: not significant; %+: percentage of positivity; RFI: relative fluorescence intensity. a Adjusted for same variables of Table 3.
