Research Article

Baseline Levels of Serum Progesterone and the First Trimester Pregnancy Outcome in Women with Threatened Abortion: A Retrospective Cohort Study

Table 3

Nonlinearity addressing of progesterone.

ExposureProgesterone (OR, 95% CI, value)

Fitting model using standard binary logistic regression model0.99 (0.98, 0.99) <0.01
Fitting model using two-piecewise regression model
 Inflection point90.62
  <inflection point0.97 (0.95, 0.98) <0.01
  ≥inflection point1.01 (0.99, 1.02) 0.27
   for log-likelihood ratio test<0.01

We used basal progesterone and adjusted for maternal age, BMI, smoking, drinking, gestational week, marital status, basal β-HCG (log10), gestity, parity, abortion, embryo visualization, cardiac movement visualization, medical history, and use of progesterone.