[Retracted] Bone Marrow Plasma Cytokine Signature Profiles in Severe Aplastic Anemia

Table 2

Statistical differences in the cytokine levels of SAA patients and HCs.

	SAA		RSAA		HC		value
	Median	Mean ± SD	Median	Mean ± SD	Median	Mean ± SD
IL-1β	0.25	0.60 ± 0.74	0.09	1.62 ± 6.04	0.40	1.19 ± 3.58	ns
IL-1ra	39.955	54.14 ± 50.87	120.72	190.63 ± 226.88	54.55	66.62 ± 54.05	0.002
IL-1ra/IL-1β	154.28	697.43 ± 1017.72	1211.00	6323.57 ± 10694.04	144.26	840.44 ± 1846.38	0.013
IL-2	1.69	2.85 ± 3.55	0.83	1.03 ± 1.02	0.605	0.63 ± 055	<0.001
IL-4	1.96	2.41 ± 1.85	2.31	2.46 ± 1.17	1.59	1.74 ± 0.63	ns
IL-7	20.17	19.99 ± 16.22	6.47	21.79 ± 47.52	10.22	15.65 ± 17.01	ns
IL-8	8.285	15.34 ± 13.80	11.46	79.21 ± 223.00	3.31	59.40 ± 182.72	ns
IL-9	10.53	19.17 ± 30.99	13.11	17.43 ± 18.61	18.69	21.50 ± 13.16	<0.001
IL-17	3.795	4.82 ± 3.26	6.84	7.15 ± 5.33	4.01	5.11 ± 2.58	ns
FGF-β	6.53	7.74 ± 4.83	5.94	7.06 ± 5.80	6.235	6.73 ± 2.61	ns
Eotaxin	52.125	64.78 ± 58.18	99.36	107.49 ± 80.50	53.415	59.07 ± 39.25	0.039
G-CSF	810.27	2518.84 ± 4163.51	84.32	191.90 ± 279.21	17.66	54.14 ± 94.76	<0.001
IFN-γ	3.56	5.19 ± 4.25	1.69	2.90 ± 3.12	1.51	1.84 ± 1.14	<0.001
IP-10	545.445	572.15 ± 356.15	442.08	460.00 ± 291.14	476.985	643.88 ± 515.86	ns
MCP-1	15.065	23.89 ± 23.02	9.47	18.36 ± 16.47	4.575	7.69 ± 8.39	<0.001
MIP-1α	2.635	3.96 ± 5.26	5.19	34.67 ± 104.49	2.31	27.57 ± 78.26	0.038
MIP-1β	26.895	32.58 ± 17.79	42.67	70.85 ± 79.20	46.32	76.94 ± 68.99	<0.001
PDGF-bb	96.85	236.80 ± 308.18	257.03	597.76 ± 1051.70	2492.395	2389.83 ± 1632.46	<0.001
RANTES	203.775	334.67 ± 366.43	1222.56	1299.58 ± 1162.78	1903.03	2027.68 ± 1201.01	<0.001
TNF-α	42.415	98.37 ± 178.04	27.96	28.16 ± 21.14	27.96	22.79 ± 17.69	0.003
IFN-γ/IL-4	1.89	2.50 ± 1.97	0.98	1.24 ± 0.84	0.885	1.13 ± 0.69	0.002

Data is presented in pg/ml; ns: not significant; SAA: severe aplastic anemia; RSAA: recovering SAA; HC: healthy control.