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BioMed Research International
/
2020
/
Article
/
Tab 2
/
Research Article
Bioavailability and Pharmacokinetics of Anisatin in Mouse Blood by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry
Table 2
Main anisatin pharmacokinetic parameters after oral and intravenous administration.
Parameters
Unit
Po (1 mg/kg)
Iv (0.5 mg/kg)
AUC
(0-
)
ng/ml × h
AUC
(0-∞)
ng/ml × h
MRT
(0-
)
h
MRT
(0-∞)
h
h
CL
z
/
F
l/h/kg
l/kg
ng/ml
Bioavailability
22.6%