Influence of Early Bladder Imaging in Experimental Rabbits on the Quantitative Determination of Glomerular Filtration Rate by the Gates Method

Figure 3

Results of dynamic renal scintigraphy in the protein load test in the rabbit. The examination was performed on the 83rd day of right ureteral obstruction; the time below each frame of the images in panels (a) and (b) indicates the start time of acquisition. (a) The phase of blood flow perfusion. (b) The phase of renal function; a small amount of urine radioactivity appeared in the bladder during 60-120 s, and much radioactivity appeared in the bladder during 120-180 s. (c) The renogram and the functional parameters. The GFR of the left kidney is 51.7 ml/min; the GFR of the right kidney is 19.9 ml/min. The left renal GFR is significantly lower than the GFR 78.6 ml/min of baseline status (Figure 2). After the renal uptake rate is corrected by bladder radioactivity, the left kidney GFR increases significantly to 88.5 ml/min, and the right kidney GFR is 20.9 ml/min. (d) The outlined ROI of the kidney and background.

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