Hypermethylation of EFEMP1 in the Hippocampus May Be Related to the Deficit in Spatial Memory of Rat Neonates Triggered by Repeated Administration of Propofol
Comparison in the methylation levels of the CpG sites in the EFEMP1 promoter region between the vehicle group and the propofol group. (a) Was the heat map representing the methylation level of CpG sites in the EFEMP1 promoter region. Every row represented the methylation level of a CpG site while every line represented the methylation level of a sample. The discrepancy in the methylation level was displayed in red or white color. The more reddish the color, the higher the methylation level. (b–f) Were used to show the comparison in the methylation level of each CpG site in the EFEMP1 promoter region between the vehicle group and the propofol group. Due to missing data in the third CpG site, no result was obtained from it. #, versus the vehicle group.
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