A Nomogram Model Based on Noninvasive Bioindicators to Predict 3-Year Risk of Nonalcoholic Fatty Liver in Nonobese Mainland Chinese: A Prospective Cohort Study

Table 1

Baseline clinical and laboratory characteristics of study population by training and validation cohort.

Characteristic	Training cohort	Validation cohort	value
No. of participants	4,605	1,550
Age (years)			0.992
ALP (U/L)			0.153
GGT (U/L)	22.00 (16.00-31.00)	22.00 (17.00-32.00)	0.287
ALT (U/L)	16.00 (12.00-22.00)	17.00 (12.00-23.00)	0.608
AST (U/L)			0.123
TP (U/L)			0.989
ALB (U/L)			0.723
GLB (U/L)			0.804
TB (mmol/L)	11.30 (8.90-14.50)	11.20 (8.90-14.30)	0.348
DBIL (mmol/L)	2.00 (1.50-2.80)	2.00 (1.40-2.70)	0.614
BUN (mmol/L)			0.534
Cr (μmol/L)			0.304
UA (μmol/L)			0.235
FPG (mmol/L)			0.45
TC (mmol/L)			0.231
TG (mmol/L)	1.14 (0.86-1.59)	1.14 (0.85-1.58)	0.793
HDL-c (mmol/L)			0.594
LDL-c (mmol/L)			0.249
BMI (kg/m^2)			0.449
SBP (mmHg)			0.574
DBP (mmHg)			0.515
Gender (, %)			0.487
Female	2033 (44.15%)	700 (45.16%)
Male	2572 (55.85%)	850 (54.84%)
Follow-up (days)			0.594
Incident NAFLD (, %)			0.783
No	3687 (80.07%)	1246 (80.39%)
Yes	918 (19.93%)	304 (19.61%)

Data are (%), , or median (interquartile range). ALP: alkaline phosphatase; GGT: γ-glutamyl transpeptidase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; TP: total protein; ALB: albumin; GLB: globulin; TB: total bilirubin; DBIL: direct bilirubin; BUN: blood urea nitrogen; Cr: creatinine; UA: uric acid; FPG: fasting plasma glucose; TC: total cholesterol; TG: triglyceride; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; NAFLD: nonalcoholic fatty liver disease.