Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors

<div>Binding interactions of compound <b>4b</b> with the active binding site of urease PDBID 4H9M generated using Discovery Studio. (a–c) Show the three-dimensional docking of derivative <b>4b</b> in a binding pocket. (d) Shows the two-dimensional ligand-protein interactions. The legend inset represents the type of interaction between the ligand atoms and the amino acid residues of the protein.</div>

BioMed Research International

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Figure 5

Figure 5: Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors 

Figure 5 | Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors 