Research Article

Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors

Table 1

Urease inhibition (IC50) values of synthesized derivatives 4a–l.

CompoundUrease (jack bean) inhibition (nM)

4a
4b
4c
4d
4e
4f
4g
4h
4i
4j
4k
4l
Thiourea