Research Article

Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors

Table 2

Kinetic parameters of the jack bean urease for urea activity in the presence of different concentrations of compound 4b.

CodeDose (μM) (ΔA/min) (mM)Inhibition type (μM) (μM)

4b0.000.0017963.076Mixed inhibition0.00070.0018
0.00080.000995.263
0.00160.000885.555