Exploring the Antitumor Mechanisms of Zingiberis Rhizoma Combined with Coptidis Rhizoma Using a Network Pharmacology Approach

Table 1

Top 20 hub targets of Zingiberis rhizoma (ZR) and Coptidis rhizoma (CR) against tumors obtained from the protein–protein interaction network.

Rank	Target name	Degree value
1	AKT1	135
2	ALB	110
3	TP53	108
4	VEGFA	106
5	EGFR	96
6	MAPK1	90
7	CASP3	86
8	JUN	83
9	ESR1	82
10	PTGS2	81
11	CCND1	73
12	MMP9	72
13	MAPK8	71
14	EP300	70
15	HSP90AA1	68
16	PPARG	66
17	NOS3	62
18	APP	57
19	AR	56
20	MMP2	54