Exploring the Antitumor Mechanisms of Zingiberis Rhizoma Combined with Coptidis Rhizoma Using a Network Pharmacology Approach

Table 4

Affinity test between component and tumor target using surface plasmon resonance (SPR) assay.

Ligand name	Analyte name	Analyte concentration	Relative response (RU)
AKT1	Berberine	1 μM	-1.7
		10 μM	4.6
		100 μM	63.8
TP53	Berberine	1 μM	0.8
		10 μM	3.4
		100 μM	22.7
EGFR	Quercetin	1 μM	5.8
		10 μM	12.4
		100 μM	77.0
VEGF165	Ginkgetin	1 μM	1.0
		10 μM	1.3
		100 μM	3.7
VEGF165	Isoginkgetin	1 μM	0.3
		10 μM	2.2
		100 μM	3.3
VEGF165	Daucosterol	1 μM	0.0
		10 μM	0.5
		100 μM	2.0
VEGF165	Quercetin	1 μM	2.5
		10 μM	3.5
		100 μM	12.1