Research Article

Predicting the Clinical Outcome of Lung Adenocarcinoma Using a Novel Gene Pair Signature Related to RNA-Binding Protein

Table 1

Prognostic signature consists of 33 RBP gene pairs.

Gene ADescriptionGene BDescriptionCoefficient

WDR46WD repeat domain 46RAE1RAE1 RNA export 1 homolog (S. pombe)-0.29314
SNRPA1Small nuclear ribonucleoprotein polypeptide APABPC1LPoly(A) binding protein, cytoplasmic 1-like0.248844
INTS8Integrator complex subunit 8SKIV2LSuperkiller viralicidic activity 2-like0.039139
DCAF13DDB1 and CUL4-associated factor 13SMAD9SMAD family member 90.048633
WDR4WD repeat domain 4PARS2Prolyl-tRNA synthetase 2, mitochondrial (putative)0.622802
MRPS12Mitochondrial ribosomal protein S12DCP1ADecapping mRNA 1A0.019737
IGF2BP1Insulin-like growth factor 2 mRNA binding protein 1PABPC3Poly(A) binding protein, cytoplasmic 30.04353
IGF2BP1Insulin-like growth factor 2 mRNA binding protein 1SRSF12Serine/arginine-rich splicing factor 120.214354
IGF2BP1Insulin-like growth factor 2 mRNA binding protein 1ZC3H12DZinc finger CCCH-type containing 12D0.047965
IGF2BP3Insulin-like growth factor 2 mRNA binding protein 3RPP40Ribonuclease P/MRP 40 kDa subunit0.030426
IGF2BP3Insulin-like growth factor 2 mRNA binding protein 3OASL2-5-oligoadenylate synthetase-like0.098828
SLU7SLU7 splicing factor homologDDX24DEAD (Asp-Glu-Ala-Asp) box polypeptide 240.295423
MAGOHBMago-nashi homolog B (Drosophila)PARS2Prolyl-tRNA synthetase 2, mitochondrial (putative)0.207791
MRPL38Mitochondrial ribosomal protein L38TSEN54tRNA splicing endonuclease 54 homolog0.1538
DDX52DEAD (Asp-Glu-Ala-Asp) box polypeptide 52STRBPSpermatid perinuclear RNA-binding protein0.012441
MRPL54Mitochondrial ribosomal protein L54OAS12-5-oligoadenylate synthetase 1, 40/46 kDa-0.05311
MRPL54Mitochondrial ribosomal protein L54DDX56DEAD (Asp-Glu-Ala-Asp) box helicase 56-0.20468
MRPL54Mitochondrial ribosomal protein L54BZW2Basic leucine zipper and W2 domains 2-0.12583
SKIV2LSuperkiller viralicidic activity 2-likeMRPS24Mitochondrial ribosomal protein S24-0.22893
SKIV2LSuperkiller viralicidic activity 2-likeDCPSDecapping enzyme, scavenger-0.11877
OAS12-5-oligoadenylate synthetase 1, 40/46 kDaPOP7Processing of precursor 7, ribonuclease P/MRP subunit0.014735
RNPC3RNA-binding region (RNP1, RRM) containing 3ERI2ERI1 exoribonuclease family member 2-0.05978
DNMT3BDNA (cytosine-5-)-methyltransferase 3 betaZC3H8Zinc finger CCCH-type containing 80.139235
SMAD9SMAD family member 9ERI2ERI1 exoribonuclease family member 2-0.09502
TDRKHTudor and KH domain containingURB1URB1 ribosome biogenesis 1 homolog-0.13488
TDRKHTudor and KH domain containingZC3HAV1LZinc finger CCCH-type, antiviral 1-like-0.01879
TDRKHTudor and KH domain containingZC3H12CZinc finger CCCH-type containing 12C-0.25482
PPIL4Peptidylprolyl isomerase (cyclophilin)-like 4DARS2Aspartyl-tRNA synthetase 2, mitochondrial-0.37219
TFB2MTranscription factor B2, mitochondrialRBPMSRNA-binding protein with multiple splicing0.029924
DARS2Aspartyl-tRNA synthetase 2, mitochondrialHINT3Histidine triad nucleotide binding protein 30.126521
PABPC3Poly(A) binding protein, cytoplasmic 3ZC3H12DZinc finger CCCH-type containing 12D0.157939
FASTKFas-activated serine/threonine kinaseSPATS2Spermatogenesis associated, serine-rich 2-like-0.04858
FASTKD3FAST kinase domains 3ZC3H12CZinc finger CCCH-type containing 12C-0.06448