Relationship between IL10 and PD-L1 in Liver Hepatocellular Carcinoma Tissue and Cell Lines

Figure 7

Effects of IL10 and crizotinib on migration and invasion on LIHC cell lines: (a, b) Western blot experiments for the effects of crizotinib and combination of IL10 and crizotinib on expression of PD-L1 and Met signal pathway in two cell lines; (c, d) effects of crizotinib and combination of crizotinib and IL10 on invasion and migration in LIHC cell lines; (e, f) effects of different concentrations of IL10 and crizotinib on invasion and migration in LIHC cell lines (0.1: concentration of IL10 was 0.1 mg/ml and crizotinib was 0.1 μM; 0.5: concentration of IL10 was 0.5 mg/ml, and crizotinib was 0.5 μM; 1: concentration of IL10 was 1 mg/ml, and crizotinib was 1 μM). compared with IL10 (0.1)+crizotinib (0.1); compared with IL10 (0.5)+crizotinib (0.5); (g, h) effects of crizotinib and combination of crizotinib and IL10 on invasion and migration of LIHC cell lines after the Met gene was knocked down in two cell lines. compared with the control group. compared with the crizotinib group. ^ compared with the crizotinib group.

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