Biological Evaluation of Newly Synthesized Biaryl Guanidine Derivatives to Arrest β-Secretase Enzymatic Activity Involved in Alzheimer’s Disease

Figure 3

Compound (9) activities have stopped the decline of the 3-D spatial learning/memory of AlCl₃-induced mouse models at some stage. The average times of explorations and the recognition indices are indicated significant with a in both cases (one-way ANOVA test). The -ratio value is 10.80; all the results are significant at ; error bars represent ; the () shows less difference while () shows a statistical significant difference.

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