Research Article
PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma
Table 1
Correlation of PBX3 expression with clinicopathologic characteristics in PTC patients.
| Clinicopathologic characteristics | | PBX3 expression (%) | value | value | Low expression | High expression |
| Total | 63 | 14 | 49 | | | Gender | | | | 0.001 | 0.971 | Male | 20 | 4 (20.0) | 16 (80.0) | | | Female | 43 | 10 (23.3) | 33 (76.7) | | | Age (years) | | | | 0.114 | 0.736 | ≤50 | 34 | 7 (20.6) | 27 (79.4) | | | >50 | 29 | 7 (24.1) | 22 (75.9) | | | Tumor size (cm) | | | | 3.375 | 0.066 | ≤1 | 27 | 9 (33.3) | 18 (66.7) | | | >1 | 36 | 5 (13.9) | 31 (86.1) | | | Histopathological grade | | | | 0.198 | 0.657 | G1 + G2 | 37 | 7 (18.9) | 30 (81.1) | | | G3 | 26 | 7 (26.9) | 19 (73.1) | | | Lymphatic metastasis | | | | 4.673 | 0.031 | Absent | 29 | 10 (34.5) | 19 (65.5) | | | Present | 34 | 4 (11.8) | 30 (88.2) | | | TMN stage | | | | 8.490 | 0.004 | T1 + T2 | 28 | 11 (39.3) | 17 (60.7) | | | T3 + T4 | 35 | 3 (8.6) | 32 (91.4) | | |
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