Research Article

PBX3 Promotes Tumor Growth and Angiogenesis via Activation of AT1R/VEGFR2 Pathway in Papillary Thyroid Carcinoma

Table 1

Correlation of PBX3 expression with clinicopathologic characteristics in PTC patients.

Clinicopathologic characteristicsPBX3 expression (%) value value
Low expressionHigh expression

Total631449
Gender0.0010.971
 Male204 (20.0)16 (80.0)
 Female4310 (23.3)33 (76.7)
Age (years)0.1140.736
 ≤50347 (20.6)27 (79.4)
 >50297 (24.1)22 (75.9)
Tumor size (cm)3.3750.066
 ≤1279 (33.3)18 (66.7)
 >1365 (13.9)31 (86.1)
Histopathological grade0.1980.657
 G1 + G2377 (18.9)30 (81.1)
 G3267 (26.9)19 (73.1)
Lymphatic metastasis4.6730.031
 Absent2910 (34.5)19 (65.5)
 Present344 (11.8)30 (88.2)
TMN stage8.4900.004
 T1 + T22811 (39.3)17 (60.7)
 T3 + T4353 (8.6)32 (91.4)