Research Article
Identification of Differentially Expressed lncRNAs and mRNAs in Children with Acquired Aplastic Anemia by RNA Sequencing
Table 2
Six immune- or hematopoietic-related DElncRNA-DEmRNA pairs.
| | mRNA | Log2FC | lncRNA | Regulation type | mRNA function |
| | DHRS9 | -2.37 | AC007556.1 | Cis/Ce | Specific and stable marker of the human regulatory macrophage | | HRH4 | -2.64 | AC007922.2 | Cis | Downregulation of Th1-related chemokines | | PDGFA | -3.05 | AC147651.1 | Cis | Promotes erythropoiesis and the proliferation of multipotent hematopoietic progenitors | | GFI1B | -2.69 | AC111000.4 | Trans | Essential protein for the normal development of the megakaryocyte lineage | | IDO1 | -4.87 | AC007991.2 | Cis | Triggers an immunosuppressive state with increased FoxP3+ Treg cells | | SEMA7A | -1.49 | RHOXF1P1 | Trans | Enhances the immunomodulatory properties of MSCs |
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