Resveratrol’s Impact on Vascular Smooth Muscle Cells Hyporeactivity: The Role of Rho-Kinase Inhibition

Table 1

Values of EC 50 and E_max in the control and test groups: resveratrol + 8Br-cGMP 0.01 M/l and 8Br-cGMP 0.1 M/l.

	n^1	EC50 (M/l)	Emax (%)^2
Control (Res−)	8	4.53 ± 1.2 × 10^−8	100.0	—
8Br-cGMP 0.01 M/l (Res−)	10	2.77 ± 0.56 × 10^−7	99.0 ± 3.0	ns^a
8Br-cGMP 0.01 M/l + resveratrol	14	3.43 ± 0.43 × 10^−7	76.4 ± 3.7
8Br-cGMP 0.1 M/l + resveratrol	12	3.43 ± 0.43 × 10^−7	61.6 ± 4.0

¹The number of CRC used for the calculation; ²E_max calculated as a % of the maximum tissue response to PHE; ^a value calculated relative to the control (Res−); ^b value calculated relative to 8Br-cGMP 0.01 M/l (Res−); ^c value calculated relative to 8Br-cGMP 0.01 M/l (Res+). All data are means ± SD.