Resveratrol’s Impact on Vascular Smooth Muscle Cells Hyporeactivity: The Role of Rho-Kinase Inhibition

Table 4

Mean values of initial pressure (p_o) and maximal pressure (p_k) induced by phenylephrine (PHE) in the control group (Res−) and test group: resveratrol + 8Br-cGMP 0.01 M/l and 8Br-cGMP 0.1 M/l.

	n^1	po (kPa)	pk (kPa)
Control (Res−)	8	4.15 ± 1.37	11.87 ± 1.33
8Br-cGMP 0.01 M/l (Res−)	10	3.28 ± 1.12	8.63 ± 0.45^a
8Br-cGMP 0.01 M/l + resveratrol	14	4.11 ± 0.63	6.33 ± 0.75^b
8Br-cGMP 0.1 M/l + resveratrol	12	2.76 ± 1.92	4.5 ± 0.68^c

¹Number of CRCs used for pressure calculations; ^a value calculated relative to control (Res−); ^b value relative to 8Br-cGMP 0.01 M/l (Res−); ^c value relative to 8Br-cGMP 0.01 M/l (Res+).