Resveratrol’s Impact on Vascular Smooth Muscle Cells Hyporeactivity: The Role of Rho-Kinase Inhibition

Table 6

Mean values of initial pressure (p_o) and maximal pressure (p_k) induced by phenylephrine (PHE) in the control group (Res−) and the test group: resveratrol + HA-1077 in concentrations 20 µM/l and 100 µM/l.

	n^1	po (kPa)	pk (kPa)
Control (Res−)	8	4.15 ± 1.37	11.87 ± 1.33
HA-1077 (20 µM/l) (Res−)	8	3.82 ± 0.83	8.32 ± 0.51^a
HA-1077 (20 µM/l) + resveratrol	12	2.52 ± 1.05	5.57 ± 0.72^b
HA-1077 (100 µM/l) + resveratrol	10	1.93 ± 1.24	3.91 ± 0.56^c

¹Number of CRCs used for pressure calculations; ^a value calculated relative to the control (Res−); ^b value calculated relative to HA-1077 (20 µM/l) (Res−); ^c value calculated relative to HA-1077 (20 µM/l) (Res+).