Resveratrol’s Impact on Vascular Smooth Muscle Cells Hyporeactivity: The Role of Rho-Kinase Inhibition

Table 7

Mean values of initial pressure (p_o) and maximal pressure (p_k) induced by phenylephrine (PHE) in the control group (Res−) and the test group: resveratrol + Bay K8644 in concentrations 0.1 mM/l and 0.01 mM/l.

	n^1	po (kPa)	pk (kPa)
Control (Res−)	8	4.15 ± 1.37	11.87 ± 1.33
Bay K8644 (0.1 mM/l) (Res−)	10	4.0 ± 1.1	13.91 ± 1.5
Bay K8644 (0.1 mM/l) + resveratrol	17	3.28 ± 1.24	10.85 ± 0.86^a
Bay k8644 (0.01 mM/l) + resveratrol	14	2.48 ± 0.82	7.69 ± 0.73^b

¹Number of CRCs used for pressure calculations; ^a value calculated in relation to Bay K8644 (0.1 mM/l) (Res−); ^b value calculated relative to Bay K8644 (0.1 mM/l) (Res+).