Genetic Diversity of HIV-1 in Krasnoyarsk Krai: Area with High Levels of HIV-1 Recombination in Russia
Table 3
Demographic characteristics of individuals infected with HIV-1 containing drug resistance mutations.
Code
Region
Age (years)
Gender
Transmission risk group
First HIV + test date
HIV-1 genotype†
PI resistance mutations
NRTI resistance mutations
NNRTI resistance mutations
Plasma HIV-1 RNA†† (copies/ml)
CD4+ cell count†† (cells/mm)3
11
Krasnoyarsk
37
F
PWID
24.07.2002
A6
K101E, E138A
1354
919
18
Krasnoyarsk
38
M
PWID
20.08.2012
A6
L210W
66400
78
29
Krasnoyarsk
32
M
PWID
28.04.2016
URF63/A
M41ML
284000
246
51
Krasnoyarsk
39
M
PWID
27.10.2015
A6
L76LV
54600
364
98
Krasnoyarsk
35
F
PWID
20.12.2013
A6
M46I
D67E, T215S
V108I
18000
597
124
Krasnoyarsk
35
M
PWID
24.02.2016
A6
M230L
5000
355
44
Krasnoyarsk
48
F
HTs
25.08.2017
URF02/A
K103N
2870
523
95
Krasnoyarsk
40
M
HTs
03.08.2017
URF63/A
V108I, E138A
840000
72
117
Krasnoyarsk
39
M
HTs
31.08.2017
CRF63_02A1
K103N
33000
445
145
Krasnoyarsk
33
F
HTs
01.11.2017
А6
K103N
34800
790
Gender: M: male; F: female. Transmission risk groups: PWID: people who inject drugs; HTs: people infected via heterosexual contacts. †HIV-1 genotype: the result of HIV-1 genotyping obtained after analysis of the complex of data: phylogenetic analysis from RP-RT, IN, and env regions and additional recombination analysis in case of inconsistency of genotyping results. ††Plasma HIV-1 RNA and CD4+ cell count detected at the time of sampling of clinical blood samples.
