Adaptive Evolution of Feline Coronavirus Genes Based on Selection Analysis

Table 4

Positive selection sites in the S gene.

Position aa	FEL p^a	REL bf^b	MEME p^a	M3 NEB pp^c	M8 BEB pp^c
22 V	-	702.524	0.028	-	-
43 H	-	-	-	1.000	0.951
101 S	-	-	-	1.000	0.981
149 T	-	-	-	0.988	0.959
151 L	-	431.458	0.046	1.000	0.997
166 R	-	-	-	1.000	0.964
167 E	-	-	-	1.000	0.999
172 T	-	114.579	0.023	1.000	0.982
175 K	-	90.617	0.011	0.964	-
229 Q	-	302.459	0.0004	-	-
245 M	0.047	96.772	0.002	1.000	0.989
475 N	-	-	-	1.000	0.977

aa: amino acid; ^a value; ^bBayes factor; ^cposterior probability. Amino acids refer to sequence KY566211.1 FCoV China. “-” represents negative results of positive selection.