Research Article
Evaluation of the Role of Human DNAJAs in the Response to Cytotoxic Chemotherapeutic Agents in a Yeast Model System
Table 4
Sensitivity of the HSP40s expressing strains to etoposide and menadione.
| | Strain | Etoposide | Menadione | | −NAc | +NAc | | Survival (% ± SEM) | Sensitivity (fold) | Survival (% ± SEM) | Sensitivity (fold) | Survival (% ± SEM) | Sensitivity (fold) |
| | ydj1Δ | 104 ± 7.7 | 1 | 10 ± 2.5 | 3.7 | 21 ± 5.7 | 2.0 | | YDJ1 | 139 ± 6.4 | 1 | 37 ± 14.5 | 1 | 41 ± 16 | 1 | | DNAJA1 | 135 ± 3.3 | 1 | 47 ± 5.0 | 0.8 | 55 ± 7.0 | 0.8 | | DNAJA2 | 184 ± 8.0 | 0.7 | 109 ± 23.0 | 0.3 | 131 ± 29 | 0.3 | | rad52Δ | 5 ± 4.8 | 29 | | | | |
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