Research Article
Evaluation of the Role of Human DNAJAs in the Response to Cytotoxic Chemotherapeutic Agents in a Yeast Model System
Table 5
Effect of DNAJA3 and DNAJA4 expression in a wild type background.
| | Strain | Doxorubicin | Heat shock | | Survival (% ± SEM) | Sensitivity (fold) | Survival (% ± SEM) | Sensitivity (fold) |
| | WT | 63.3 ± 18.6 | 1 | 104 ± 4 | 1 | | WT-DNAJA3 | 20 ± 2.9 | 3.2 | 0 ± 0 | — | | WT-DNAJA4 | 4 ± 1.8 | 15.8 | 0 ± 0 | — |
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