Increased Temperature Facilitates Adeno-Associated Virus Vector Transduction of Colorectal Cancer Cell Lines in a Manner Dependent on Heat Shock Protein Signature

Figure 7

AAVR, HSPG1 and HSPG2 expression in CRC lines. The influence of heat shock on the expression of genes in tested cells as well normal cells was estimated by the reverse transcription and the qPCR method. The cells not exposure to hyperemia were used as reference to calculate fold range (2^−ΔΔCt). Statistically significant differences were analyzed between cells incubated at 37°C and cells exposed to hyperthermia conditions (; ).