Circulating Exosomal SOCS2-AS1 Acts as a Novel Biomarker in Predicting the Diagnosis of Coronary Artery Disease

Table 4

The clinical relevance analysis of SOCS2-AS1 expression levels in CAD patients.

Feather	Lower expression (n = 62)	Higher expression (n = 22)	value
Age (years)			0.778
≤60	15	4
>60	47	18
Gender			0.176
Male	38	17
Female	24	5
Smoking			0.904
Yes	12	4
No	50	18
Hypertension			0.622
Yes	43	14
No	19	8
Diabetes			0.861
Yes	21	7
No	41	15
Lesion artery number			0.154
Single	23	12
Multi	39	10
Severity of artery stenosis			0.569
Severe	44	17
Slight	18	5
CRP (mg/L)	13.87 ± 28.43	9.93 ± 15.45	0.538
PLT (10^9/L)	182.37 ± 50.77	141.50 ± 47.39	0.001^&
FIB (g/L)	2.63 ± 0.92	2.43 ± 0.86	0.384
INR	1.04 ± 0.76	1.08 ± 0.78	0.053
BUN (mmol/L)	5.95 ± 2.15	6.51 ± 2.68	0.331
Cr (μmol/L)	83.22 ± 47.97	116.94 ± 159.77	0.340
FBG (mmol/L)	6.44 ± 2.10	7.71 ± 4.02	0.169
UA (μmol/L)	350.92 ± 79.42	341.82 ± 88.51	0.655
TC (mmol/L)	4.34 ± 1.05	4.06 ± 1.02	0.275
TG (mmol/L)	2.13 ± 2.21	1.83 ± 1.10	0.544
HDL-C (mmol/L)	1.27 ± 0.30	1.25 ± 0.25	0.793
LDL-C (mmol/L)	2.31 ± 0.74	2.11 ± 0.74	0.292
Lpa (mg/L)	267.75 ± 228.25	179.85 ± 275.71	0.146

CRP: C-reaction protein; PLT: Platelet; FIB: Fibrinogen; INR: International Normalized Ratio; BUN: Blood Urea Nitrogen; Cr: Creatinine; FBG: Fasting Blood Glucose; UA: Uric Acid; TC: Total Cholesterol; TG: Triglyceride; HDL-C: High Density Lipoprotein-cholesterol; LDL-C: Low Density Lipoprotein-cholesterol; Lpa: Lipoprotein a. .