Research Article
Circulating Exosomal SOCS2-AS1 Acts as a Novel Biomarker in Predicting the Diagnosis of Coronary Artery Disease
Table 4
The clinical relevance analysis of SOCS2-AS1 expression levels in CAD patients.
| Feather | Lower expression (n = 62) | Higher expression (n = 22) | value |
| Age (years) | | | 0.778 | ≤60 | 15 | 4 | | >60 | 47 | 18 | |
| Gender | | | 0.176 | Male | 38 | 17 | | Female | 24 | 5 | |
| Smoking | | | 0.904 | Yes | 12 | 4 | | No | 50 | 18 | |
| Hypertension | | | 0.622 | Yes | 43 | 14 | | No | 19 | 8 | |
| Diabetes | | | 0.861 | Yes | 21 | 7 | | No | 41 | 15 | |
| Lesion artery number | | | 0.154 | Single | 23 | 12 | | Multi | 39 | 10 | |
| Severity of artery stenosis | | | 0.569 | Severe | 44 | 17 | | Slight | 18 | 5 | | CRP (mg/L) | 13.87 ± 28.43 | 9.93 ± 15.45 | 0.538 | PLT (109/L) | 182.37 ± 50.77 | 141.50 ± 47.39 | 0.001& | FIB (g/L) | 2.63 ± 0.92 | 2.43 ± 0.86 | 0.384 | INR | 1.04 ± 0.76 | 1.08 ± 0.78 | 0.053 | BUN (mmol/L) | 5.95 ± 2.15 | 6.51 ± 2.68 | 0.331 | Cr (μmol/L) | 83.22 ± 47.97 | 116.94 ± 159.77 | 0.340 | FBG (mmol/L) | 6.44 ± 2.10 | 7.71 ± 4.02 | 0.169 | UA (μmol/L) | 350.92 ± 79.42 | 341.82 ± 88.51 | 0.655 | TC (mmol/L) | 4.34 ± 1.05 | 4.06 ± 1.02 | 0.275 | TG (mmol/L) | 2.13 ± 2.21 | 1.83 ± 1.10 | 0.544 | HDL-C (mmol/L) | 1.27 ± 0.30 | 1.25 ± 0.25 | 0.793 | LDL-C (mmol/L) | 2.31 ± 0.74 | 2.11 ± 0.74 | 0.292 | Lpa (mg/L) | 267.75 ± 228.25 | 179.85 ± 275.71 | 0.146 |
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CRP: C-reaction protein; PLT: Platelet; FIB: Fibrinogen; INR: International Normalized Ratio; BUN: Blood Urea Nitrogen; Cr: Creatinine; FBG: Fasting Blood Glucose; UA: Uric Acid; TC: Total Cholesterol; TG: Triglyceride; HDL-C: High Density Lipoprotein-cholesterol; LDL-C: Low Density Lipoprotein-cholesterol; Lpa: Lipoprotein a. . |