Evaluation of Acid-Modified Ethiopian Potato (Plectranthus edulis) Starch as Directly Compressible Tablet Excipient

Table 1

Paracetamol tablet formulations containing spray-dried NEPS, spray-dried AMEPS, and S1500® as a directly compressible excipient at four levels of concentration.

Ingredients (%)	Formulations
	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12
Paracetamol	20	30	40	50	20	30	40	50	20	30	40	50
SdNEPS	75.5	65.5	55.5	45.5	—	—	—	—	—	—	—	—
SdAMEPS	—	—	—	—	75.5	65.5	55.5	45.5	—	—	—	—
S1500®	—	—	—	—	—	—	—	—	75.5	65.5	55.5	45.5
CCS	4	4	4	4	4	4	4	4	4	4	4	4
Magnesium stearate	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5	0.5

CCS: croscarmellose sodium. S_dNEPS and S_dAMEPS stand for spray-dried native and acid-modified Ethiopian potato starch, respectively.