Research Article

Associations between Aquaglyceroporin Gene Polymorphisms and Risk of Stroke among Patients with Hypertension

Table 1

Demographic and clinical characteristics by cases with stroke and controls.

VariablesCases with stroke (%)Controls (%)

Degree of education
 Primary school and below157 (74.4%)436 (68.9%)0.291
 Junior high school47 (22.3%)167 (26.4%)
 High school and above7 (3.3%)30 (4.7%)
Duration of hypertension (years)
 ≤5122 (60.7%)416 (69.6%)0.020
 >579 (39.3%)182 (30.4%)
Familial history of hypertension48 (23.1%)102 (16.3%)0.029
Familial history of stroke10 (4.8%)11 (1.7%)0.014
Familial history of CHD7 (3.4%)11 (1.8%)0.167
Familial history of diabetes5 (2.4%)11 (1.7%)0.556
Central obesity158 (74.9%)480 (75.8%)0.781
BMI (kg/m2)
 Normal78 (37.0%)243 (38.4%)0.922
 Overweight89 (42.2%)264 (41.7%)
 Obese44 (20.9%)126 (19.9%)
SBP (mmHg)0.012
DBP (mmHg)0.071
TC (mmol/L)0.006
TG (mmol/L)0.019
FBG (mmol/L)0.023
HDL-C (mmol/L)0.130
LDL-C (mmol/L)0.652

represents . SD: standard deviation; CHD: coronary heart disease; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: triglycerides; FBG: fasting blood glucose; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.