A Comparative Study of 2 Different Segmentation Methods of ADC Histogram for Differentiation Genetic Subtypes in Lower-Grade Diffuse Gliomas

Table 5

Comparison of ADC histogram parameters of the two different ROIs between IDH^wt gliomas and IDH^mut gliomas.

Values (×10^-6 mm^2/s)	IDH^wt group,	IDH^mut group,	Test values	values
ADCmean^1		1419.95 (1279.30, 1565.89)	-1.796^b	0.073
ADCmean^2		1341.13 (1242.53, 1547.90)	-0.109^b	0.913
ADCmin^1			-3.067^a	0.006
ADCmin^2			-4196^a	<0.001
P5 ADC^1		1010.00 (929.86, 1094.88)	-0.852^b	0.394
P5 ADC^2		1009.00 (913.75, 1076.75)	-2.648^b	0.008
P10 ADC^1		1073.25 (987.88, 1161.63)	-0.381^b	0.703
P10 ADC^2		1069.50 (970.75, 1173.75)	-1.904^b	0.057
P25 ADC^1		1205.75 (1104.88, 1336.38)	-0.689^b	0.491
P25 ADC^2		1178.50 (1081.50, 1331.75)	-1.904^b	0.301
P50 ADC^1		1352.75 (1255.63, 1586.38)	-1.560^b	0.119
P50 ADC^2		1320.50 (1225.00, 1547.25)	-01.109^b	0.913
P75 ADC^1		1586.50 (1411.63, 1764.75)	-2.385^b	0.017
P75 ADC^2		1481.50 (1356.50, 1749.00)	-0.580^b	0.562
P90 ADC^1		1815.25 (1615.50, 2003.50)	-2.430^b	0.015
P90 ADC^2			0.953^a	0.345
P95 ADC^1			2.415^a	0.025
P95 ADC^2			1.135^a	0.261
ADCmax^1		2716.50 (2161.63, 3409.75)	-2.195^b	0.028
ADCmax^2			1.242^a	0.220
ADCmode^1		1285.00 (1139.50, 1619.25)	-1.324^b	0.185
ADCmode^2		1273.50 (1142.25, 1610.25)	-0.517^b	0.605
Kurtosis^1	-0.527 (-1.027, 0.480)	0.661 (-0.397, 2.273)	-2.721^b	0.007
Kurtosis^2		-0.126 (-0.374, 0.304)	-2.512^b	0.012
Skewness^1			-0.979^a	0.332
Skewness^2			-0.955^a	0.344
StDev^1	388.630 (343.670, 689.60)	278.864 (217.080, 357.755)	-3.156^b	0.002
StDev^2			4.110^a	<0.001
Inhomogenity^1		0.190 (0.160, 0.231)	-3.347^b	0.001
Inhomogenity^2			6.048^a	<0.001
Range^1		1941.25 (1406.00, 2788.38)	-2.721^b	0.007
Range^2			2.991^a	0.004
Entropy^1			0.218^a	0.825
Entropy^2			0.798^a	0.428

¹ROI-1; ²ROI-2; ^a value; ^b value.