Research Article
A Comparative Study of 2 Different Segmentation Methods of ADC Histogram for Differentiation Genetic Subtypes in Lower-Grade Diffuse Gliomas
Table 7
ROC Curve analysis of different parameters for distinguishing IDHwt gliomas from IDHmut gliomas.
| Parameter | ROI | AUC | Specificity (%) | Sensitivity (%) | Cutoff value | value |
| ADCmin | ROI-1 | 0.749 | 87.5 | 62.5 | 560.00 | 0.180 | ROI-2 | 0.831 | 90.0 | 62.5 | 543.00 |
| P5 ADC | ROI-1 | — | — | — | — | — | ROI-2 | 0.728 | 57.5 | 81.2 | 980.00 |
| P75 ADC | ROI-1 | 0.705 | 68.8 | 70.0 | 1688.25 | — | ROI-2 | — | — | — | — |
| P90 ADC | ROI-1 | 0.709 | 68.8 | 77.5 | 1962.00 | — | ROI-2 | — | — | — | — |
| P95 ADC | ROI-1 | 0.709 | 68.8 | 72.5 | 2164.75 | — | ROI-2 | — | — | — | — |
| ADCmax | ROI-1 | 0.689 | 81.3 | 57.5 | 2849.00 | — | ROI-2 | — | — | — | — |
| Kurtosis | ROI-1 | 0.734 | 87.5 | 56.2 | -0.487 | 0.826 | ROI-2 | 0.716 | 47.5 | 87.5 | -0.042 |
| StDev | ROI-1 | 0.772 | 87.5 | 65.0 | 321.702 | 0.646 | ROI-2 | 0.803 | 68.8 | 80.0 | 272.351 |
| Inhomogenity | ROI-1 | 0.788 | 81.3 | 75.0 | 0.229 | 0.013 | ROI-2 | 0.930 | 93.8 | 82.5 | 0.186 |
| Range | ROI-1 | 0.734 | 81.3 | 60.0 | 2144.5 | 0.838 | ROI-2 | 0.747 | 68.8 | 82.5 | 1977.5 |
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