Risk Factors of Portal Vein Thrombosis after Devascularization Treatment in Patients with Liver Cirrhosis: A Nested Case-Control Study
Table 3
Univariate analysis of risk factors for thrombosis during follow-up.
Factor
PVT ()
Without PVT ()
Age (years old)
0.859
First bleeding time from surgery (years)
0.4 (0.17~0.80)
0.4 (0.20-1.00)
0.649 (0.766)
Meld score
0.120
Spleen length (cm)
0.126
Spleen width (cm)
0.742
Spleen thickness (cm)
6 (5~6.5)
6 (5-6)
0.802 (0.594)
Red blood cell (×1012/L)
0.987
Hemoglobin (g/L)
0.903
White blood cell (×109/L)
0.423
Platelet (×109/L)
0.968
Total bilirubin (μmol/L)
0.779
Conjugated bilirubin (μmol/L)
6.7 (5.4~10.5)
5.8 (4.7~7.8)
0.394 (0.614)
Albumin (g/L)
0.067
Alanine aminotransferase (U/L)
0.684
Aspartate aminotransferase (U/L)
0.881
Creatinine (μmol/L)
0.051
Urea (mmol/L)
5.2 (3.4~7.1)
4.7 (3.8~5.3)
0.650 (0.687)
Uric acid (μmol/L)
0.361
Activated partial thromboplastin time (s)
0.287
International normalization ratio
0.395
Thrombin time (s)
0.694
Prothrombin time (s)
0.169
Fibrinogen (mg/dL)
0.625
Portal vein diameter (mm)
0.068
Portal vein flow rate (m/s)
0.580
Postoperative platelets (×109/L)
0.536
Platelet differences between preoperative and postoperative (×109/L)
0.486
Postoperative portal vein trunk diameter (mm)
11 (10~12)
11 (10~12)
0.367 (0.548)
Postoperative portal vein trunk flow rate (m/s)
0.545
Spleen volume (cm3)
0.272
Previous history of endoscopic treatment
No
12 (63.2%)
28 (77.8%)
0.177
Yes
7 (36.8%)
8 (22.2%)
Child-Pugh grade
A
15 (78.9%)
24 (68.6%)
0.416
B
4 (21.1%)
11 (31.4%)
Gender
Female
8 (42.1%)
12 (34.3%)
0.520
Male
11 (57.9%)
23 (65.7%)
Abdominal surgery history
No
17 (89.5%)
31 (88.6%)
1.0
Yes
2 (10.5%)
4 (11.4%)
Combined devascularization
No
7 (36.8%)
10 (25.7%)
0.392
Yes
12 (63.2%)
26 (74.3%)
Peripheral blood vessel dissection
No
12 (70.9%)
26 (74.3%)
0.392
Yes
7 (36.8%)
10 (25.7%)
Hypertension
No
15 (78.9%)
33 (94.3%)
0.169
Yes
4 (21.1%)
2 (5.7%)
Diabetes
No
14 (73.7%)
31 (88.6%)
0.251
Yes
5 (26.3%)
4 (11.4%)
Smoking
No
17 (89.5%)
31 (88.6%)
1.0
Yes
2 (10.5%)
4 (11.4%)
History of blood transfusion
No
9 (47.4%)
20 (57.1%)
0.492
Yes
10 (52.6%)
15 (42.9%)
Grade of splenomegaly
0
4 (21.1%)
16 (45.7%)
0.046 (0.160)
I
4 (21.1%)
6 (17.1%)
II
1 (5.3%)
4 (11.4%)
III
10 (52.6%)
9 (25.7%)
Grade of esophageal varices
No
1 (5.3%)
0 (0%)
0.229 (0.170)
Mild
0 (0%)
1 (2.9%)
Moderate
1 (5.3%)
8 (22.9%)
Severe
17 (89.5%)
26 (74.3%)
With gastric varices
No
7 (36.8%)
13 (37.1%)
0.983
Yes
12 (63.2%)
22 (62.9%)
Ascites
No
14 (73.7%)
26 (74.3%)
1
Yes
5 (26.3%)
9 (25.7%)
Hepatic encephalopathy
No
18 (94.7%)
35 (100%)
0.352
Yes
1 (5.3%)
0
Posthepatitic cirrhosis
No
8 (42.1%)
15 (42.9%)
0.957
Yes
11 (57.9%)
20 (57.1%)
using the K–S test for data that were not normally distributed. Nonparametric tests were used to compare the groups. The results of Student’s -test are also included. Graded variables. The rank-sum test was used to compare the groups, and the chi-square test results are also included.