Abnormal Levels of Liver Enzymes and Hepatotoxicity in HIV-Positive, TB, and HIV/TB-Coinfected Patients on Treatment in Fako Division, Southwest Region of Cameroon
Table 1
Baseline characteristics of the study population stratified by treatment groups.
Variable
Subclass
HIV (%)
TB (%)
TB/HIV (%)
Total (%)
value
Gender
Female
46 (60.5)
15 (46.9)
07 (41.2)
68 (54.4)
3.0787
0.214
Male
30 (39.5)
17 (53.1)
10 (58.8)
57 (45.6)
Age (years)
<40
34 (44.7)
22 (68.8)
6 (35.3)
62 (49.6)
6.8051
0.332
≥40
42 (55.3)
10 (31.2)
11 (64.7)
63 (50.4)
Mean age (±SD)
BMI
Underweight
04 (5.3)
05 (15.6)
01 (5.9)
10 (8.00)
7.4444
0.11418
Normal
40 (52.6)
20 (62.5)
12 (70.6)
72 (57.6)
Overweight
32 (42.1)
07 (21.9)
04 (23.5)
43 (34.4)
Mean BMI (±SD)
Education
NFE+primary
23 (30.3)
10 (31.2)
06 (35.3)
39 (31.2)
7.7285
0.102046
Secondary
41 (53.9)
11 (34.4)
05 (29.4)
57 (45.6)
Tertiary
12 (15.8)
11 (34.4)
06 (35.3)
29 (23.2)
Marital status
Married
28 (36.8)
11 (34.4)
06 (35.3)
45 (36.0)
0.0637
0.968
Unmarried
48 (63.2)
21 (65.6)
11 (64.7)
80 (64.0)
Occupation
Skilled
13 (17.1)
02 (6.3)
03 (17.6)
18 (12.8)
11.6556
0.070109
Unskilled
54 (71.1)
22 (68.8)
12 (70.6)
88 (72.0)
Student
03 (3.9)
07 (21.8)
2 (11.8)
12 (9.60)
Unemployed
06 (7.9)
01 (3.1)
00 (0.00)
07 (5.60)
WHO clinical stage
Stage 0
00 (0.0)
32 (100.0)
00 (0.00)
32 (25.6)
Stage 1
18 (23.7)
00 (0.00)
04 (23.5)
22 (17.6)
Stage 2
39 (51.3)
00 (0.00)
06 (35.3)
45 (36.0)
Stage 3
19 (25.0)
00 (0.00)
07 (41.2)
26 (20.8)
BCG scar
Yes
44 (57.9)
20 (62.5)
09 (52.9)
73 (58.4)
0.4379
0.80335
No
32 (42.1)
12 (37.5)
08 (47.1)
52 (41.6)
LNE
Yes
0 (0.0)
0 (0.0)
2 (11.8)
2 (1.6)
No
76 (100.0)
32 (100.0)
15 (88.2)
123 (98.4)
Type of TB
Pulmonary
00 (0.0)
27 (84.4)
16 (94.1)
43 (34.4)
Extrapulmonary
00 (0.0)
05 (15.6)
01 (5.9)
06 (4.8)
Negative
76 (100)
00 (0.0)
00 (00.0)
76 (60.8)
OI
Yes
31 (40.8)
00 (0.0)
03 (17.6)
34 (27.2)
No
45 (59.2)
32 (100.0)
14 (82.4)
91 (72.8)
Malaria
Yes
17 (22.4)
12 (37.5)
07 (41.2)
36 (28.8)
3.9842
0.136
No
59 (77.6)
20 (62.5)
10 (58.8)
89 (71.2)
Total
OI = opportunistic infection; NFE = no formal education.
