Abnormal Levels of Liver Enzymes and Hepatotoxicity in HIV-Positive, TB, and HIV/TB-Coinfected Patients on Treatment in Fako Division, Southwest Region of Cameroon

Table 2

Association of hepatotoxicity with possible risk factors.

Variables		Abnormal liver enzymes		Total (%)		value
		Yes (%)	No (%)
Gender	Male	24 (45.3)	44 (61.1)	68 (54.4)	3.0831	0.79108
	Female	29 (54.7)	28 (38.9)	57 (45.6)
Age range	<40	26 (49.1)	36 (50.0)	62 (49.6)	0.0109	0.916969
	≥40	27 (50.9)	36 (50.0)	63 (50.4)
Drug regimens	ATD	12 (22.6)	20 (27.8)	32 (25.6)	1.0908	0.57962
	HAART	32 (60.4)	44 (61.1)	76 (60.8)
	ATD/HAART	9 (17.0)	8 (11.1)	17 (13.6)
Malaria	Yes	16 (30.2)	21 (29.2)	37 (29.6)	0.0153	0.901552
	No	37 (69.8)	51 (70.8)	89 (71.2)
Opportunistic infection	Yes	15 (28.3)	18 (25.0)	34 (26.4)	0.1352	0.7131
	No	38 (71.7)	54 (75.0)	92 (73.6)
Alcoholism	Yes	13 (24.5)	17 (23.6)	30 (24.0)	0.8778	0.644749
	Ex-drinker	28 (52.8)	28 (38.9)	56 (44.8)
	No	12 (22.7)	27 (37.5)	39 (31.2)
Smoking	Yes	1 (1.9)	1 (1.4)	2 (1.60)	0.7927	0.672788
	Ex-smoker	6 (11.3)	5 (6.9)	11 (8.80)
	No	46 (86.8)	66 (91.7)	112 (89.6)
Total (%)		53 (42.4)	72 (57.6)	125 (100)