The Immune Cell Landscape in Different Anatomical Structures of Knee in Osteoarthritis: A Gene Expression-Based Study

Table 2

Comparison of immune cell abundance in osteoarthritis subchondral bones and osteoarthritis synovial tissues calculated by xCell and CIBERSORT algorithms.

	Cell type	xCell score	Correlation between xCell and CIBERSORT		Qualitative consistency xCell vs. CIBERSORT
			Correlation coefficient	value
Subchondral bone	Neutrophils		0.602	<0.001	Yes
Synovial tissue	Plasma cells		0.555	<0.001	Yes
	Macrophage M1		-0.087	0.410	No
	Macrophage M2		0.233	0.026	Yes
	Eosinophils		0.075	0.479	Yes

Qualitative consistency without statistical significance.