DNA Primase Subunit 1 Expression in Hepatocellular Carcinoma and Its Clinical Implication

Table 3

Univariate and multivariate analyses of clinicopathological factors for OS in HCC.

Clinical characteristics	HR	value
Univariate analysis
Sex (male vs. female)	1.47 (0.90-2.42)	0.126
BMI (<25 kg/m^2 vs. ≥25 kg/m^2)	1.24 (0.76-2.03)	0.384
Stage (I-II vs. III-IV)	1.54 (0.88-2.68)	0.131
Grade (G1-G2 vs. G3-G4)	1.39 (0.85-2.27)	0.191
Age (<55 y vs. ≥55 y)	1.38 (0.80-2.36)	0.247
AFP (≤400 ng/ml vs. >400 ng/ml)	1.02 (0.58-1.79)	0.938
Platelet (10^3/mm^3)	1.00 (1.00-1.00)	0.377
Race (Asian vs. non-Asian)	2.22 (1.30-3.77)	0.003
PRIM1 expression (high vs. low)	1.32 (1.06-1.65)	0.014
Multivariate analysis
Race (Asian vs. non-Asian)	2.21 (1.30-3.76)	0.006
PRIM1 expression (high vs. low)	1.31 (1.06-1.62)	0.027

Notes: BMI: body mass index; AFP: alpha-fetoprotein; PRIM1: DNA Primase Subunit 1.